BDBM50240868 7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one::CHEMBL350475::OSTHENOL

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])ccc2ccc(=O)oc12

InChI Key InChIKey=RAKJVIPCCGXHHS-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50240868   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50240868(7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataKi:  260nMAssay Description:Competitive inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240868(7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50240868(7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50:  740nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50240868(7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50240868(7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50240868(7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using benzylamine as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed