BDBM50197063 4,6-dioxoheptanoic acid::CHEMBL222824::succinylacetone
SMILES CC(=O)CC(=O)CCC(O)=O
InChI Key InChIKey=WYEPBHZLDUPIOD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50197063
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181-426) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BBOX1 by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PHD2 expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human FIH expressed in Escherichia coli by MALDI assayMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of human KDM6B catalytic domain expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair