BDBM50359629 TROLOX

SMILES Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O

InChI Key InChIKey=GLEVLJDDWXEYCO-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50359629   

TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto Superior Técnico

LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50:  4.00E+6nMpH: 8.0Assay Description:AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto Superior Técnico

LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50:  1.86E+5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human plasmatic BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyung Hee University Skin Biotechnology Center

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of mushroom tyrosinase activity using L-tyrosin as substrate after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50:  150nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDehydrogenase/reductase SDR family member 9(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of 3alphaHSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50:  130nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50:  1.31E+4nMAssay Description:Anti-oxidant activity in DPPH radical scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed