BDBM454223 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(dimethylcarbamoyl)phenyl)-2-methyl- 1H-indole-5-carboxylic acid::US10717733, Compound 16::US11098045, Compound 16
SMILES CN(C)C(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O
InChI Key InChIKey=KJKWDAGGVYNCGG-NVMNQCDNSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 454223
Affinity DataIC50: >3.00E+3nMAssay Description:Mao-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c...More data for this Ligand-Target Pair