BDBM50538668 CHEMBL4634455::US11518761, Example 159

SMILES Nc1ncnc2n(nc(Oc3cc(ccn3)C(F)(F)F)c12)C1CC1

InChI Key InChIKey=KWGARBYHIQLXRK-UHFFFAOYSA-N

Data  4 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538668   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)
Affinity DataIC50:  13nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)
Affinity DataIC50:  16.5nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent