BDBM50584319 CHEMBL5085536::US20230303540, Example Ex-1.24

SMILES Clc1c(Nc2ncc3cc(Cl)c(cc3n2)N2CCN(CC2)C2COC2)cnn1C1CC1

InChI Key InChIKey=VHWGHMXATMWDPG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50584319   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50584319(CHEMBL5085536 | US20230303540, Example Ex-1.24)
Affinity DataIC50:  2.59nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent