BDBM317539 6-chloro-3-[(1S)-1-{[3-(2-methylpropyl)-2-oxo-2H,3H-[1,3]oxazolo[4,5-d]pyrimidin-5-yl]amino}ethyl]-1,2-dihydroquinolin-2-one::US9624175, Compound I-55
SMILES CC(C)Cn1c2nc(N[C@@H](C)c3cc4cc(Cl)ccc4[nH]c3=O)ncc2oc1=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 317539
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [1-390,401-414,R132C](Human)
Forma Therapeutics
US Patent
Forma Therapeutics
US Patent
Affinity DataIC50: <100nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair