BDBM283215 4-[2-(4-amino-piperidin-1-yl)-5- (4-methoxyphenyl)-1-methyl-6-oxo- 1,6-dihydro-pyrimidin-4-yl]- 2-fluorobenzonitrile::US10023543, Example 6::US10207999, Example 6::US10328077, Example 6::US10548896, Example 6::US10849898, Example 6::US10960005, Example 6::US11084793, Example 6::US9573930, Example 6::US9771329, Example 6::US9776974, Example 6
SMILES COc1ccc(cc1)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=WRSMRGFIRPWKHU-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 283215
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair