BDBM283217 4-[2-(4-amino-piperidin-1-yl)-5- (6-methoxypyridin-3-yl)-1- methyl-6-oxo-1,6-dihydro- pyrimidin-4-yl]-2-fluoro- benzonitrile::US10023543, Example 8::US10207999, Example 8::US10328077, Example 8::US10548896, Example 8::US10849898, Example 8::US10960005, Example 8::US11084793, Example 8::US9573930, Example 8::US9771329, Example 8::US9776974, Example 8
SMILES COc1ccc(cn1)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=OFYGKLHDEFAIDM-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 283217
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair