BDBM352613 (S)-tert-butyl (2-(2- amino-2-oxoethyl)-4- ((3-(trifluoromethyl) phenyl)sulfonyl)- 3,4-dihydro-2H-benzo [b][1,4]oxazin-6- yl)carbamate::US10745364, Example 37B::US9809561, 37B

SMILES CC(C)(C)OC(=O)Nc1ccc2O[C@@H](CC(N)=O)CN(c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=YQHZTSNBZXYWAZ-HNNXBMFYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352613   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352613((S)-tert-butyl (2-(2- amino-2-oxoethyl)-4- ((3-(tr...)
Affinity DataIC50:  3.66nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent