BDBM136833 US10231967, Example 73::US8865911, 73::US9000182, 21, isomer 1::US9918985, Example 73
SMILES CC#Cc1cncc(c1)-c1ccc2C[C@@]3(CC[C@H](O)CC3)[C@]3(N=C(C)C(N)=N3)c2c1
InChI Key InChIKey=NVGRJZRZTUKQGI-TUSQITKMSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 136833
Affinity DataIC50: 1.30nMAssay Description:The β-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human β-Secretase (AA 1-AA 460) was...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair