BDBM50498453 CHEMBL3596862
SMILES COc1ccc(cc1)-c1cncc(Oc2cccc(NC(=O)Nc3cc(on3)C(C)(C)C)c2)n1
InChI Key InChIKey=LTTAHJWMYYUXHI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50498453
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of KDR (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair