BDBM50500894 CHEMBL3799578
SMILES Fc1ccc(CNc2ccnc(n2)N2CCC3(CCN(CC4CCCN4)C3)CC2)c(F)c1
InChI Key InChIKey=FSDWNJPKSHXSJP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50500894
TargetC-C chemokine receptor type 4(Human)
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Displacement of [125I]-TARC from human recombinant CCR4 expressed in CHO cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Human)
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at human CCR4 expressed in CHO cells by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Human)
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Induction of CCR4 internalisation in human HUT78 cells after 30 mins by flow cytometryMore data for this Ligand-Target Pair