BDBM50232678 CHEBI:27413::CHEMBL1618272::US10717734, Compound BAPN::US11098045, Compound BAPN

SMILES NCCC#N

InChI Key InChIKey=AGSPXMVUFBBBMO-UHFFFAOYSA-N

Data  34 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50232678   

TargetAmine oxidase [flavin-containing] B(Human)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >3.00E+3nMAssay Description:Mao-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50:  398nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Bovine)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized low-density lipoprotein receptor 1(Bovine)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >1.00E+3nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: <1.00E+3nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetMembrane primary amine oxidase(Human)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >3.00E+3nMAssay Description:Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >3.00E+3nMAssay Description:MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetOxidized low-density lipoprotein receptor 1(Bovine)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >1.00E+6nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: <1.00E+6nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetMembrane primary amine oxidase(Human)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >3.00E+3nMAssay Description:SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >3.00E+3nMAssay Description:MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetOxidized low-density lipoprotein receptor 1(Bovine)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >1.00E+3nMAssay Description:LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: <1.00E+3nMAssay Description:LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetMembrane primary amine oxidase(Human)
Pharmaxis

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: >3.00E+3nMAssay Description:Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c...More data for this Ligand-Target Pair
In DepthDetails US Patent