BDBM116257 US10035794, Example 34::US10683287, Example 34::US8637508, 34
SMILES C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(NC(=O)c2ncc(cc2Cl)C(F)(F)F)ccc1F
InChI Key InChIKey=PSBBWFNMHDUTRH-DLBZAZTESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 116257
Affinity DataIC50: 30nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 in CHO cells expressing human APP assessed as reduction in amyloidbeta (1 to 40 residues) level incubated for 24 hrs by immunoass...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair