BDBM370419 2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol::US10233190, Example 1254

SMILES OCCC1c2ccccc2-c2cncn12

InChI Key InChIKey=VQGLVXRSMONFQT-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370419   

TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM370419(2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol | US1023...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human TDO using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed