BDBM50437206 CHEMBL2402737

SMILES COc1cc(ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@](C#N)([C@H]1c1cccc(Cl)c1F)c1ccc(Cl)cc1F)C(O)=O

InChI Key InChIKey=TVTXCJFHQKSQQM-LJQIRTBHSA-N

Data  2 IC50  3 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437206   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Wisconsin-Madison

Curated by ChEMBL

LigandBDBM50437206(CHEMBL2402737)Copy SMILESCopy InChI

Affinity DataIC50:  6nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI