BDBM50079455 CHEMBL46486::tetramethylammonium

SMILES C[N+](C)(C)C

InChI Key InChIKey=QEMXHQIAXOOASZ-UHFFFAOYSA-N

Data  9 KI  4 IC50

PDB links: 11 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079455   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept

Curated by ChEMBL

LigandBDBM50079455(CHEMBL46486 | tetramethylammonium)Copy SMILESCopy InChI

Affinity DataKi:  24nMAssay Description:Binding affinity at heteropentameric Nicotinic acetylcholine receptor alpha4-beta2 subtype using [3H]-bungarotoxin as radioligandMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL

LigandBDBM50079455(CHEMBL46486 | tetramethylammonium)Copy SMILESCopy InChI

Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity at homopentameric Nicotinic acetylcholine receptor alpha7 subtype using [3H]-S-(-)-nicotine as radioligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI