BDBM22952 CHEMBL73572::Indomethacin derivative, 5::methyl 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetate
SMILES COC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12
InChI Key InChIKey=OKHORWCUMZIORR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 22952
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:In vitro inhibitory activity against ovine Prostaglandin G/H synthase 1 (44 nM) using [14C]AA (50 uM) was determinedMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (66 nM) using [14C]-AA (50 uM) was determinedMore data for this Ligand-Target Pair