BDBM50007203 CHEMBL3237875

SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=WQAVPPWWLLVGFK-VTNASVEKSA-N

Data  56 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007203   

TargetProteasome subunit beta type-9(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of LMP2 in human 20S immunoproteasome using Ac-PAL-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Beta1 subunit in human 20S proteasome using Ac-nLPnLD-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  38nMAssay Description:Inhibition of LMP7 in human 20S immunoproteasome using Ac-ANW-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  473nMAssay Description:Inhibition of Beta5 in human 20S immunoproteasome usingAc-WLA-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed