BDBM50546218 CHEMBL4741490::US11466016, Example 114
SMILES [H][C@]12CC[C@]([H])([C@@H](F)[C@@H](N)C1)N2c1nc2[nH]nc(-c3ccc4ncsc4c3Cl)c2nc1CO
InChI Key InChIKey=WZKPKLAFWZONRV-XJFVKYJOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50546218
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Allosteric inhibition of SHP2 (unknown origin) using DiFMUP as substrate preincubated for 30 mins in presence of activating peptide [IRSl_pY1172(dPEG...More data for this Ligand-Target Pair