BDBM12915 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one::2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one::CHEMBL98350::LY294002::US10308662, Compound LY294002::US9505780, LY294002

SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1

InChI Key InChIKey=CZQHHVNHHHRRDU-UHFFFAOYSA-N

Data  8 KI  148 IC50  1 Kd

PDB links: 5 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12915   

TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL

LigandBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)Copy SMILESCopy InChI

Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of DNA-dependent protein kinase (DNA-PK) of HeLa cell nuclear cell extractMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
CHEMBLDrugBankMCE
KEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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