BDBM50559469 CHEMBL4788469
SMILES CN1c2ccccc2C(=O)N(C)c2cnc(N[C@H]3CC[C@H](O)CC3)cc12
InChI Key InChIKey=XDCQYSVFUPULSL-HDJSIYSDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50559469
Affinity DataEC50: 2.11E+3nMAssay Description:Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced TNFalpha secretion preincubated for 1 hr followed by LPS-stimulation and measur...More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant human ERK5 using myelin basic protein as substrate by [gamm33P]ATP based HotSpot radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.99E+3nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of ERK5 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Binding affinity to BRD4-BD1 (unknown origin)More data for this Ligand-Target Pair