BDBM4703 4-carboxybenzenesulfonamide 1::4-sulfamoylbenzoic acid::Benzoic Acid deriv. 31::CHEMBL414::JMC522226 Compound 22::JMC523116 Compound 22::JMC52646 Compound 23::aromatic/heteroaromatic sulfonamide 23

SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key InChIKey=UCAGLBKTLXCODC-UHFFFAOYSA-N

Data  95 KI  9 IC50  2 Kd

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 4703   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of recombinant human CA1 using 4-nitrophenylacetate as substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant human CA2 using 4-nitrophenylacetate as substrate by esterase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of recombinant human CA9 using 4-nitrophenylacetate as substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed