BDBM408711 3-(methoxymethyl)-1-({4-[(2-oxopyridin-1-yl)methyl]phenyl}methyl)-N-{[4- (trifluoromethyl)pyridin-3-yl]methyl}pyrazole-4-carboxamide ::US10364238, Example 31::US10364238, Example 37::US11001578, Example 37::US11084809, Example 37::US11198691, Example 37

SMILES COCc1nn(Cc2ccc(Cn3ccccc3=O)cc2)cc1C(=O)NCc1cnccc1C(F)(F)F

InChI Key InChIKey=ZHJJZIGZXRDDHP-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408711   

TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM408711(3-(methoxymethyl)-1-({4-[(2-oxopyridin-1-yl)methyl...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human plasma kallikrein using H-D-Pro-Phe-Arg-AFC as flurogenic substrate preincubated for 5 mins followed by substrate addition by flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed