BDBM50140172 CHEBI:3962::CHEMBL140::Curcumin::US9409845, Table 1, Compound 21: curcumin
SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
InChI Key InChIKey=VFLDPWHFBUODDF-FCXRPNKRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50140172
Affinity DataIC50: 900nMAssay Description:Inhibition of amyloid beta (unknown origin) incubated for 7 days by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of amyloid beta 40 (unknown origin) assessed as disaggregation of fibrillar amyloid beta 40 incubated for 3 days by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair