BDBM50325818 2-(2'-(trifluoromethoxy)biphenyl-3-yl)thiazole-4-carboxamide::CHEMBL1224655
SMILES NC(=O)c1csc(n1)-c1cccc(c1)-c1ccccc1OC(F)(F)F
InChI Key InChIKey=MNJFIVNZRQTGJX-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50325818
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Blockade of human Nav1.7 by voltage ion probe reader based FRET assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Blockade of human Nav1.7 by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 8.79E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair