BDBM50349297 CHEMBL1808456::CHEMBL1813104
SMILES CS(=O)(=O)c1cc(Cl)c(NC(=O)N2CCn3c(C2)c(O)n([C@H]2C[C@@H]2c2ccccc2)c3=O)c(Cl)c1
InChI Key InChIKey=WTXGNYIYUYYEQU-QAPCUYQASA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50349297
Affinity DataIC50: 41nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair