BDBM50229322 (3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methoxy)benzamido)-1-(prop-2-ynyl)pyrrolidine-3-carboxamide::CHEMBL271235
SMILES Cc1cc(COc2ccc(cc2)C(=O)N[C@@H]2CN(CC#C)C[C@@H]2C(=O)NO)c2ccccc2n1
InChI Key InChIKey=SIICAQVADMFEDB-LADGPHEKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50229322
TargetMacrophage metalloelastase(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity to MMP12More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Binding affinity to MMP10More data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Binding affinity to MMP13More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataKi: 1.72E+3nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Binding affinity to MMP8More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Binding affinity to MMP14More data for this Ligand-Target Pair
Affinity DataKi: >4.95E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-15(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataKi: >7.10E+3nMAssay Description:Binding affinity to MMP15More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair