BDBM50380728 CHEMBL2017835

SMILES Cc1cc(C)cc(C[C@H]2CCCCN2C(=O)CN2c3ccccc3-n3c(nnc3-c3ccccc3)[C@H](Cc3n[nH]c4ccccc34)C2=O)c1

InChI Key InChIKey=ZJGPYSQTJSMQNL-BHYZAODMSA-N

Data  8 KI  32 IC50  11 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50380728   

TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50380728(CHEMBL2017835)
Affinity DataEC50:  25.4nMAssay Description:Agonist activity at human CCK1 receptor assessed as increase in CCK8-induced calcium release incubated in dark for 30 mins followed by light incubati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50380728(CHEMBL2017835)
Affinity DataIC50:  14.7nMAssay Description:Displacement of [125I]-CCK-2 from rat CCK1 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50380728(CHEMBL2017835)
Affinity DataIC50:  20.3nMAssay Description:Displacement of [125I]-CCK-2 from human CCK1 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed