BDBM50069103 CHEMBL3403509::US10189853, Compound 2

SMILES COc1ccc(N(C)c2nc(C)nc3oc(C)cc23)c(OC)c1

InChI Key InChIKey=ZTPYIOAESPUXFH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069103   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50069103(CHEMBL3403509 | US10189853, Compound 2)
Affinity DataIC50:  40nMAssay Description:Inhibition of PDGFR-beta in human U251 cells compound pretreated for 60 min before PDGF-BB stimulation for 10 mins by phosphotyrosine ELISA cytoblot ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50069103(CHEMBL3403509 | US10189853, Compound 2)
Affinity DataIC50:  32nMAssay Description:Inhibition of VEGFR2 in human U251 cells compound pretreated for 60 min before VEGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50069103(CHEMBL3403509 | US10189853, Compound 2)
Affinity DataIC50:  162nMAssay Description:Inhibition of EGFR in human A431 cells compound pretreated for 60 min before EGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed