BDBM50156760 (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide::2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide::2-{[(1-(2-hydroxy-naphthalen-1-yl)meth-(E)-ylidene]amino}-N-(1-phenylethyl)-benzamide::2-{[1-(2-hydroxynaphthalen-1-yl)meth-(E)-ylene]amino}-N-(1-phenylethyl)benzamide::CHEMBL380797::Sirtinol
SMILES CC(NC(=O)c1ccccc1\N=C\c1c(O)ccc2ccccc12)c1ccccc1
InChI Key InChIKey=UXJFDYIHRJGPFS-WPWMEQJKSA-N
Data 38 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50156760
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Guru Jambheshwar University Of Science And Technology
Curated by ChEMBL
Guru Jambheshwar University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of recombinant yeast Sir2p using acetylated HeLa histones as substrate measured after 2 hrs in presence of NAD by scintillation counting m...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology
Curated by ChEMBL
Guru Jambheshwar University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human GST-tagged SIRT1 (18 to 340 residues) expressed in Escherichia coli BL21 (DE3)LysS using acetylated HeLa histones as substrate me...More data for this Ligand-Target Pair