BDBM50193395 Altiratinib::DCC-2701::DP-5164
SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2cc(F)c(Oc3ccnc(NC(=O)C4CC4)c3)cc2F)cc1
InChI Key InChIKey=GNNDEPIMDAZHRQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50193395
Affinity DataIC50: 4.60nMAssay Description:Inhibition of TrkB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
St. John'S University
Curated by ChEMBL
St. John'S University
Curated by ChEMBL
Affinity DataIC50: 0.850nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of TIE-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of TrkC (unknown origin)More data for this Ligand-Target Pair