BDBM86632 JNK-IN-7

SMILES CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2cccnc2)cc1

InChI Key InChIKey=RADRIIWGHYFWPP-UHFFFAOYSA-N

Data  22 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86632   

TargetMitogen-activated protein kinase 10(Human)
Harvard Medical School

LigandChemical structure of BindingDB Monomer ID 86632BDBM86632(JNK-IN-7)
Affinity DataIC50: 0.75nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Harvard Medical School

LigandChemical structure of BindingDB Monomer ID 86632BDBM86632(JNK-IN-7)
Affinity DataIC50: 1.54nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Harvard Medical School

LigandChemical structure of BindingDB Monomer ID 86632BDBM86632(JNK-IN-7)
Affinity DataIC50: 1.99nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed