BDBM202391 US10081606, Compound I-23::US9238629, I-23::US9765038, Compound I-23

SMILES COc1cccc(Nc2ncc(c(Oc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC

InChI Key InChIKey=HIMGGUFXIBERNV-UHFFFAOYSA-N

Data  6 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 202391   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM202391(US10081606, Compound I-23 | US9238629, I-23 | US97...)
Affinity DataEC50: >1.00E+3nMAssay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM202391(US10081606, Compound I-23 | US9238629, I-23 | US97...)
Affinity DataIC50:  20nMpH: 7.5Assay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM202391(US10081606, Compound I-23 | US9238629, I-23 | US97...)
Affinity DataIC50: >1.00E+3nMAssay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-249,301-1210,T790M,L858R](Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM202391(US10081606, Compound I-23 | US9238629, I-23 | US97...)
Affinity DataIC50:  20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM202391(US10081606, Compound I-23 | US9238629, I-23 | US97...)
Affinity DataIC50: >1.00E+3nMpH: 7.5Assay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent