BDBM179894 US10287250, Compound C.12::US9133125, Table C, Compound 12
SMILES CN1CC[C@]23[C@H](CCC[C@H]2C1)Oc1c3cccc1C(N)=O
InChI Key InChIKey=SZOGKPIPCIDKSZ-YLVFBTJISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 179894
Affinity DataKi: 23nM ΔG°: -10.4kcal/mole IC50: >3.00E+3nMpH: 7.5 T: 25°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:The EC50 and Imax for μ opioid receptors was determined using a [35S]GTPγS binding assay. This assay measures the functional properties of ...More data for this Ligand-Target Pair
Affinity DataEC50: 190nMpH: 7.4Assay Description:The EC50 and Imax for μ opioid receptors was determined using a [I35S]GTPγS binding assay. This assay measures the functional properties of a compo...More data for this Ligand-Target Pair