BDBM113298 US10336717, Compound 76::US8633212, 76::US9212153, 76

SMILES COC1CCC2(Cc3ccc(cc3C22N=C(N)N(C)C2=O)C#CC2CC2)CC1

InChI Key InChIKey=USHFPDQMSUANTM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 113298   

TargetBeta-secretase 1 [1-458](Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM113298(US10336717, Compound 76 | US8633212, 76 | US921215...)
Affinity DataIC50:  2.10nMpH: 4.5 T: 2°CAssay Description:Inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE activity using commercially available substrate HiLyte Fluor 488...More data for this Ligand-Target Pair
In DepthDetails US Patent