BDBM50434169 CHEMBL2385300::US9346814, Cmpd No 22 Example 26

SMILES Brc1cccc2nccc(C(=O)NCC(=O)N3CCC[C@H]3C#N)c12

InChI Key InChIKey=XTSDSKNXFWPJCS-NSHDSACASA-N

Data  1 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50434169   

TargetDipeptidyl peptidase 4(Human)
Universiteit Antwerp

US Patent
LigandPNGBDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 37°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetDipeptidyl peptidase 9(Human)
Universiteit Antwerp

US Patent
LigandPNGBDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 37°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetDipeptidyl peptidase 2(Human)
Universiteit Antwerp

US Patent
LigandPNGBDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 37°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProlyl endopeptidase(Human)
Universiteit Antwerp

US Patent
LigandPNGBDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataIC50: >5.00E+4nMpH: 8.3 T: 37°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProlyl endopeptidase FAP(Mouse)
Universiteit Antwerp

US Patent
LigandPNGBDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataIC50:  11nMpH: 8.3 T: 37°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent