BDBM50398716 CHEMBL2179618::US10227295, Compound 5g::US9409858, 5g::US9751832, Compound 5g::US9956192, Compound 5g

SMILES CCCCN(Cc1ccc(cc1)C(=O)NO)C(=O)Nc1ccccc1

InChI Key InChIKey=JZWXMCPARMXZQV-UHFFFAOYSA-N

Data  4 KI  75 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398716   

TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)
Affinity DataIC50:  3.02E+3nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)
Affinity DataIC50:  5.02nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails US Patent