BDBM385122 US10287267, Compound 278::US10508099, Compound 278::US10556885, Compound 278::US11174244, Compound 278::US11673881, Compound 278
SMILES Cn1cnnc1-c1ccc2cnc(NC(=O)C3CCN(CCC(F)(F)F)CC3)cc2c1
InChI Key InChIKey=YMKJOTYFJVWVBL-UHFFFAOYSA-N
Data 12 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 385122
Affinity DataEC50: 413nMAssay Description:SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed
US Patent
Samumed
US Patent
Affinity DataEC50: 3.20nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves ...More data for this Ligand-Target Pair