BDBM50383382 CHEMBL2030556::CHEMBL2069948::US10172858, Table 2.9::US10544104, Compound 26::US11247972, Compound 26::US9765037, Compound 26::US9828378, # 9

SMILES CC(C)n1nc(-c2cc3c(Cl)cccc3[nH]2)c2c(N)ncnc12

InChI Key InChIKey=XVLBYYUDKFJBBH-UHFFFAOYSA-N

Data  2 KI  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50383382   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For

US Patent
LigandPNGBDBM50383382(CHEMBL2030556 | CHEMBL2069948 | US10172858, Table ...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University of Washington Through Its Center For

US Patent
LigandPNGBDBM50383382(CHEMBL2030556 | CHEMBL2069948 | US10172858, Table ...)
Affinity DataIC50:  16.2nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Washington Through Its Center For

US Patent
LigandPNGBDBM50383382(CHEMBL2030556 | CHEMBL2069948 | US10172858, Table ...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Washington Through Its Center For

US Patent
LigandPNGBDBM50383382(CHEMBL2030556 | CHEMBL2069948 | US10172858, Table ...)
Affinity DataIC50:  304nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent