BDBM385221 US10287267, Compound 487::US10508099, Compound 487::US10556885, Compound 487::US11174244, Compound 487::US11673881, Compound 487

SMILES Cn1cc(nn1)-c1ccc2cnc(NC(=O)CN3CCCC3)cc2c1

InChI Key InChIKey=RYGDYORLQXUCIN-UHFFFAOYSA-N

Data  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 385221   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385221(US10287267, Compound 487 | US10508099, Compound 48...)
Affinity DataEC50:  7.70nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions. This is a non-radioactive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385221(US10287267, Compound 487 | US10508099, Compound 48...)
Affinity DataEC50:  7nMAssay Description:GSK3B: This is a non-radioactive assay using fluorescence resonance energy transfer (FRET) between coumarin and fluorescein to detect kinase activity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent