BDBM384442 US10590114, No. 128::US11111235, No. 128::US11591316, Compound 128::US9932325, Example 128

SMILES CNc1nc(Nc2cc(nn2C2CC2)C(C)(C)c2ncccn2)ncc1C(F)(F)F

InChI Key InChIKey=MRJSOUDBGKNLAQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384442   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Denali Therapautics

US Patent
LigandPNGBDBM384442(US10590114, No. 128 | US11111235, No. 128 | US1159...)
Affinity DataIC50: <30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent