BDBM50511356 CHEMBL4537890::US10988478, Example 385
SMILES CN1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2S1(=O)=O)N1CCOCC1
InChI Key InChIKey=KWGTXAZLFBSTGA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50511356
Affinity DataKi: 19nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair