BDBM50095027 (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol (M 100907)::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol(MDL 100907)::(R)-(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol::(R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(R)-(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::(R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol::CHEMBL74355::MDL 100907::MDL-100907
SMILES COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC
InChI Key InChIKey=HXTGXYRHXAGCFP-OAQYLSRUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50095027
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Binding affinity for displacement of [3H]ketanserin to rat 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:Ability of the compound to displace [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor was determinedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.310nMAssay Description:Binding affinity for displacement of [3H]ketanserin to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.360nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor in humansMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]MDL100907 from rat cortical membrane 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyserMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.570nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKd: 0.140nMAssay Description:Binding affinity to human brain homogenate 5-HT2A assessed as dissociation constant by quantitative autoradiographic analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair