BDBM429691 5-(3-(4-(4- chlorophenyl) piperidin-1- yl)-2-methyl- 3-oxopropyl)- 5-methyl imidazolidine- 2,4-dione::US10550100, Compound 24

SMILES C[C@@H](C[C@@]1(C)NC(=O)NC1=O)C(=O)N1CCC(CC1)c1ccc(Cl)cc1

InChI Key InChIKey=DVMYRZMUQOTBGR-HXPMCKFVSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429691   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM429691(5-(3-(4-(4- chlorophenyl) piperidin-1- yl)-2-methy...)
Affinity DataIC50:  75nMAssay Description:The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by human ADAMTS-5.For the dose res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent