BDBM429691 5-(3-(4-(4- chlorophenyl) piperidin-1- yl)-2-methyl- 3-oxopropyl)- 5-methyl imidazolidine- 2,4-dione::US10550100, Compound 24
SMILES C[C@@H](C[C@@]1(C)NC(=O)NC1=O)C(=O)N1CCC(CC1)c1ccc(Cl)cc1
InChI Key InChIKey=DVMYRZMUQOTBGR-HXPMCKFVSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 429691
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: 75nMAssay Description:The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by human ADAMTS-5.For the dose res...More data for this Ligand-Target Pair