BDBM98282 US8481733, 94

SMILES COc1cc(Oc2ccccc2)ccc1-c1nc([C@H]2C[C@@](C)(O)C2)n2ccnc(N)c12

InChI Key InChIKey=PILAMBNAJPBLFA-RWXRFDSASA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 98282   

TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98282(US8481733, 94)
Affinity DataIC50:  119nMAssay Description:AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98282(US8481733, 94)
Affinity DataIC50:  110nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98282(US8481733, 94)
Affinity DataIC50:  35nMAssay Description:Inhibition of ACK1 kinase (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98282(US8481733, 94)
Affinity DataIC50:  110nMAssay Description:Inhibition of ACK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98282(US8481733, 94)
Affinity DataIC50:  35nMAssay Description:Inhibition of ACK1 (unknown origin) by cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed