BDBM19188 7-(3-chlorobenzyloxy)-4-(methylamino)methyl-coumarin, 2::7-[(3-chlorophenyl)methoxy]-4-[(methylamino)methyl]-2H-chromen-2-one::C18::CHEMBL593763
SMILES CNCc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12
InChI Key InChIKey=JMGUSOLCNQVZCT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 19188
Affinity DataKi: 100nM ΔG°: -9.54kcal/molepH: 7.5 T: 2°CAssay Description:MAO B activities were determined spectrophotometrically at 250 nm using benzylamine as substrate. Competitive Ki values were determined by measuring ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of MAO-B from Wistar rat brain by radioenzymatic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of MAO-B from Wistar rat brain by radioenzymatic assay in presence of human platelet rich plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B in brain mitochondrial homogenate assessed as 4-hydroxyquinoline by spectrophotometric methodMore data for this Ligand-Target Pair