BDBM50193395 Altiratinib::DCC-2701::DP-5164

SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2cc(F)c(Oc3ccnc(NC(=O)C4CC4)c3)cc2F)cc1

InChI Key InChIKey=GNNDEPIMDAZHRQ-UHFFFAOYSA-N

Data  13 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193395   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50193395(Altiratinib | DCC-2701 | DP-5164)
Affinity DataIC50:  8nMAssay Description:Inhibition of TIE-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50193395(Altiratinib | DCC-2701 | DP-5164)
Affinity DataIC50:  8nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed