BDBM50089038 CGP 71683::CGP-71683A::CHEMBL17645::N-{[(1r,4r)-4-{[(4-aminoquinazolin-2-yl)amino]methyl}cyclohexyl]methyl}naphthalene-1-sulfonamide (Compound 1)::Naphthalene-1-sulfonic acid {4-[(4-amino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-amide

SMILES Nc1nc(NC[C@H]2CC[C@H](CNS(=O)(=O)c3cccc4ccccc34)CC2)nc2ccccc12

InChI Key InChIKey=UULIGRNKXHCLQN-WGSAOQKQSA-N

Data  2 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089038   

TargetAquaporin-1(Human)
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM50089038(CGP 71683 | CGP-71683A | CHEMBL17645 | N-{[(1r,4r)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed